In 2001, President-elect Ralph Nader, who had been chosen by the people in the biggest election shocker in a century, was assassinated before he could assume office.
President-elect Nader AssassinatedAlthough there was some constitutional question about it, the Vice-President-elect, Nader's running mate Winona LaDuke, took the oath of office later that month and became the first woman president in American history.
Wikipedia reports - Winona (meaning "first daughter" in Ojibwe) LaDuke was born in 1959 in Los Angeles, California, to Vincent and Betty (Bernstein) LaDuke. Her father, an Anishinaabe (Ojibwe) from White Earth Reservation in Minnesota, enrolled his daughter as a member of the tribe at an early age. As a young man, he had been an activist on treaty rights and tribal issues, particularly the loss of lands. The reservation was one-tenth of its original size, and the losses contributed to unemployment and other problems of its people.